Collage with a person in lab coat, a cell and figures
(© iFit)
Clusters of Excellence

Image-guided and Functionally Instructed Tumor Therapies

The Cluster of Excellence 2180 "Image-guided and Functionally Instructed Tumor Therapies" (iFIT) is the only oncology cluster of excellence in Germany. Since 2019, internationally renowned scientists and talented young researchers have been working together in this consortium in a globally unique collaboration of three different research areas to develop new, individualized cancer therapies.

The iFIT Cluster of Excellence „Image Guided and Functionally Instructed Tumor Therapies (iFIT)“ aims to achieve a comprehensive understanding of biological processes in tumors in order to develop innovative and sustainable cancer therapies. Previously available cancer therapies have often proven to be ineffective in the long term. Although modern drug-based cancer therapies are now also succeeding in containing the disease in patients with advanced tumor diseases, resistance is almost always developing. The tumors begin to grow again despite therapy. The researchers therefore want to comprehensively analyze the biological processes in tumors by means of functional genetic testing and identify possible weak points that could represent targets for new drugs. The cluster has identified three key research areas for this purpose:

  •   Functional target identification and molecular tumor therapies
  •   Immunotherapy
  •  Molecular and functional multiparametric imaging

Involved Institutions:

  • Deutsches Krebsforschungszentrum (DKFZ) Deutsches Konsortium für Translationale Krebsforschung
  • Robert Bosch Gesellschaft für medizinische Forschung mbH
  • Max-Planck-Institut für Biologie
  • NMI Naturwissenschaftliches und Medizinisches Institut an der Universität Tübingen
  • Max-Planck-Institut für Intelligente Systeme


Podcast on the Cluster of Excellence

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